Deputy District Attorney Mickey Thacker said two cases before Nelson and three before Smith have a high possibility of being heard.
Among those the court could potentially sound first is that of Allen Scott Martin, who is accused in the death of his roommate, Roy David Owens.
In September 2009, Owens' body was found behind a trash bin at Bartow Motel, 803 Joe Frank Harris Parkway, Cartersville. Martin was arrested at that time and charged with murder, concealing the death of another and tampering with evidence.
Police alleged Martin caused Owens' death by blunt force trauma to the head and then moved the body to the woods behind the bin before cleaning up the room.
The men had been roommates at the motel, and at the time of Owens' death, Cartersville police said there was no indication drugs or alcohol were involved.
Martin faces counts of murder, felony murder and concealing the death of another.
According to Thacker, Martin's trial may not begin until Tuesday.
Along with Martin, Nelson also could hear the case of Jeremy D'Andre Dent, Kierre Demone Johnson and Larry Leroy Kirby.
Dent faces five counts of aggravated assault, two counts of second-degree criminal damage to property - special presentment, deadly weapons at public gathering and carrying a concealed weapon. Johnson and Kirby each face five counts of aggravated assault and two counts of second-degree criminal damage to property - special presentment.
In Smith's courtroom, the cases likely to be heard include:
* Jennifer Ann Guelberg, Lamont Marcellus Wynn and Delano Navine Sfale -- Each face one count of possession of cocaine with intent to distribute.
* Franklin Delonore Johnson -- One count of burglary.
* Eduardo Osorio -- One count of trafficking in methamphetamine.
Thacker said if all five cases -- the two for Nelson and three for Smith -- go to trial, the proceedings could take all week.